Session 1. An Impact of Sleep Research: Models from Molecule to Behavior
Prostaglandins and Sleep
O. Hayaishi
African Sleeping Sickness and the Nervous System
V.W. Pentreath
The Chemistry and Biology of Oleamides: A Sleep Inducing Lipid
B.F. Cravatt

Session 2. Neuronal Activities during Sleep
Neuromodulated Sleep Circuitries That Determine Behavioral Issues
M.H. Chase
Modulation of Cholinergic Neurons by Serotonin and Adenosine in the Control of REM and non-REM Sleep
R.W. McCarley
A Possible Mechanism of Dynamics-Transition of Central Single Neuronal Activity during Sleep
M. Yamamoto

Session 3. Evolution of Sleep
The Evolution of Waking States
R.V. Rial
Sleep in Monotremes
J. Siegel
Physiological and Biochemical Approach to Hibernation Control Mechanism in Mammalian Hibernators
N. Kondo

Session 4. Homeostasis and Aging of Sleep
Sleep Regulation in Humans - New Perspectives
A.A. Borbely
Daytime Sleepiness in Normals: Individual Defferences in Sleep Need Not Affect Ability to Fall Asleep
T. Roth
Sleep-Wake Rhythm Disorders in Elderly Patients with Dementia
Y. Hishikawa

Session 5. Hormones and Sleep
Modulatory Role of Sleep on Hormonal Pulsatility
G. Brandenberger
Melatonin Regulation of Sleep-Wake and Gonado-Pituitary Rhythms in Humans
P. Lavie
Sleep and Melatonin Rhythm in Humans
K. Honma

Session 6. Host Defense and Sleep
Sleep-Wakefulness and Immune-Neuroendocrine Functions in Humans
H. Moldofsky
Cytokines in Sleep Regulation
J.M. Krueger

Session 7. Molecular Biological Approach to Sleep Research
Role of the Ventrolateral Preoptic Area in Sleep Induction
C.B. Saper
Sleep, Sleep Regulation and Circadian Rest-Activity Rhythm in Prion Protein Knockout Mice
I. Tobler

Session 8. Genetics of Sleep Disorders
Fatal Familial Insomnia
E. Lugaresi
Pathophysiological and Genetical Aspects of Narcolepsy
E. Mignot
Genetics of Narcolepsy
Y. Honda

Session 9. Cognitive Functions of Dreaming Brain
Visual Skill Consolidation in the Dreaming Brain
J. Askenasi
Thalamic Mechanisms in Sleep Control
M. Mancia
Functional Meaning of Sleep and Dream: A Physiologist's Thought
M. Ito

Session 10. Closing Remarks
A Function of Sleep: Neuronal Detoxification in the Brain
S. Inoue
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